956348-61-1

956348-61-1 structure
956348-61-1 structure
  • Name: Propargyl-PEG-amine
  • Chemical Name: 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-Tetracosaoxapentaheptacont-74-yn-1-amine
  • CAS Number: 956348-61-1
  • Molecular Formula: (C2H4O)nC5H9NO
  • Molecular Weight: 1112.340
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-01-10 13:05:08
  • Modify Date: 2024-01-16 11:47:14
  • Propargyl-PEG-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-Tetracosaoxapentaheptacont-74-yn-1-amine
Synonyms MFCD30723251
3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-Tetracosaoxapentaheptacont-74-yn-1-amine
Description Propargyl-PEG-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Density 1.1±0.1 g/cm3
Boiling Point 911.7±60.0 °C at 760 mmHg
Molecular Formula (C2H4O)nC5H9NO
Molecular Weight 1112.340
Flash Point 479.1±26.6 °C
Exact Mass 1111.671387
LogP -8.34
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.469
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