1049740-32-0

1049740-32-0 structure

Name: A-331440 dihydrochloride
Chemical Name: A 331440 dihydrochloride
CAS Number: 1049740-32-0
Molecular Formula: C₂₂H₂₉Cl₂N₃O
Molecular Weight: 422.39
Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
Create Date: 2021-04-30 23:35:27
Modify Date: 2025-09-18 20:32:39
A 331440 hydrochloride is a histamine H3 receptor antagonist. A 331440 hydrochloride binds potently and selectively to human and rat histamine H3 receptors (Ki≤25 nM). A 331440 hydrochloride can be used for antiobesity research[1].

Name	A 331440 dihydrochloride
Synonyms	A-331440 dihydrochloride [1,1'-Biphenyl]-4-carbonitrile, 4'-[3-[(3R)-3-(dimethylamino)-1-pyrrolidinyl]propoxy]-, hydrochloride (1:2) MFCD08705336 4'-{3-[(3R)-3-(Dimethylamino)-1-pyrrolidinyl]propoxy}-4-biphenylcarbonitrile dihydrochloride 4'-[3-[(3(R)-Dimethylamino-1-pyrrolidinyl]propoxy]-[1,1-biphenyl]-4'-carbonitrile dihydrochloride

Description	A 331440 hydrochloride is a histamine H3 receptor antagonist. A 331440 hydrochloride binds potently and selectively to human and rat histamine H3 receptors (Ki≤25 nM). A 331440 hydrochloride can be used for antiobesity research[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
References	[1]. Hancock AA, et al. Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist. Eur J Pharmacol. 2004 Mar 8;487(1-3):183-97.