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1135416-11-3

1135416-11-3 structure
1135416-11-3 structure
  • Name: Z-DEVD-AFC
  • Chemical Name: Z-DEVD-AFC
  • CAS Number: 1135416-11-3
  • Molecular Formula: C36H38F3N5O14
  • Molecular Weight: 821.707
  • Catalog: Signaling Pathways Apoptosis Caspase
  • Create Date: 2021-05-01 23:06:26
  • Modify Date: 2024-01-06 20:10:40
  • Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity[1].

Name Z-DEVD-AFC
Synonyms N-[(Benzyloxy)carbonyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-N-[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]-L-α-asparagine
L-α-Asparagine, N-[(phenylmethoxy)carbonyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-
Z-DEVD-AFC
Description Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity[1].
Related Catalog
References

[1]. Santiago AR, et al. High glucose induces caspase-independent cell death in retinal neural cells. Neurobiol Dis. 2007;25(3):464-472.

Density 1.5±0.1 g/cm3
Boiling Point 1160.9±65.0 °C at 760 mmHg
Molecular Formula C36H38F3N5O14
Molecular Weight 821.707
Flash Point 655.9±34.3 °C
Exact Mass 821.236755
LogP 4.15
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.591