263849-50-9

263849-50-9 structure

Name: 1-Benzoyl-2-[[trans-4-[[[[2-nitro-4-(trifluoromethyl)phenyl]sulfonyl]amino]methyl]cyclohexyl]carbonyl]hydrazine
Chemical Name: S 25585
CAS Number: 263849-50-9
Molecular Formula: C₂₂H₂₃F₃N₄O₆S
Molecular Weight: 528.501
Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
Create Date: 2021-05-12 19:03:37
Modify Date: 2025-08-26 06:17:56
S 25585 is a potent and selective neuropeptide Y (NPY) Y5 receptor antagonist. S 25585 reduces food intake but not through blockade of the NPY Y5 receptor[1].

Name	S 25585
Synonyms	EINECS 263-849-5 Benzoic acid, 2-[[trans-4-[[[[2-nitro-4-(trifluoromethyl)phenyl]sulfonyl]amino]methyl]cyclohexyl]carbonyl]hydrazide N-({trans-4-[(2-Benzoylhydrazino)carbonyl]cyclohexyl}methyl)-2-nitro-4-(trifluoromethyl)benzenesulfonamide

Description	S 25585 is a potent and selective neuropeptide Y (NPY) Y5 receptor antagonist. S 25585 reduces food intake but not through blockade of the NPY Y5 receptor[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor
References	[1]. Della-Zuana O, et al. A potent and selective NPY Y5 antagonist reduces food intake but not through blockade of the NPY Y5 receptor. Int J Obes Relat Metab Disord. 2004 Apr;28(4):628-39.