1332184-63-0
1332184-63-0 structure
- Name: IL-4-inhibitor-1
- Chemical Name: IL-4 Inhibitor
- CAS Number: 1332184-63-0
- Molecular Formula: C18H12FN3O2
- Molecular Weight: 321.31
- Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
- Create Date: 2021-06-13 06:49:59
- Modify Date: 2024-01-11 15:36:30
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IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM[1].
| Name | IL-4 Inhibitor |
|---|---|
| Synonyms |
3-Pyridinecarbonitrile, 2-amino-4-(3,4-dihydroxyphenyl)-6-(4-fluorophenyl)-
IL-4 Inhibitor 2-Amino-4-(3,4-dihydroxyphenyl)-6-(4-fluorophenyl)nicotinonitrile |
| Description | IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM[1]. |
|---|---|
| Related Catalog | |
| Target |
EC50: 1.81 µM (IL-4)[1]. |
| In Vitro | IL-4-inhibitor-1 (compound 52) displays low micromolar affinity and exhibits functional disruption of type II IL-4 binding in a cellular context[1]. IL-4-inhibitor-1 (compound 52) exhibits dose-dependent reduction in pSTAT-6 levels with an EC50 value of 3.1 µM, but did not affect the levels of STAT-6[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 590.6±50.0 °C at 760 mmHg |
| Molecular Formula | C18H12FN3O2 |
| Molecular Weight | 321.31 |
| Flash Point | 311.0±30.1 °C |
| Exact Mass | 321.091370 |
| LogP | 3.17 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.729 |