IL-4-inhibitor-1
Modify Date: 2024-01-11 15:36:30
IL-4-inhibitor-1 structure
|
Common Name | IL-4-inhibitor-1 | ||
|---|---|---|---|---|
| CAS Number | 1332184-63-0 | Molecular Weight | 321.31 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 590.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C18H12FN3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 311.0±30.1 °C | |
Use of IL-4-inhibitor-1IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM[1]. |
| Name | IL-4 Inhibitor |
|---|---|
| Synonym | More Synonyms |
| Description | IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM[1]. |
|---|---|
| Related Catalog | |
| Target |
EC50: 1.81 µM (IL-4)[1]. |
| In Vitro | IL-4-inhibitor-1 (compound 52) displays low micromolar affinity and exhibits functional disruption of type II IL-4 binding in a cellular context[1]. IL-4-inhibitor-1 (compound 52) exhibits dose-dependent reduction in pSTAT-6 levels with an EC50 value of 3.1 µM, but did not affect the levels of STAT-6[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 590.6±50.0 °C at 760 mmHg |
| Molecular Formula | C18H12FN3O2 |
| Molecular Weight | 321.31 |
| Flash Point | 311.0±30.1 °C |
| Exact Mass | 321.091370 |
| LogP | 3.17 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.729 |
| 3-Pyridinecarbonitrile, 2-amino-4-(3,4-dihydroxyphenyl)-6-(4-fluorophenyl)- |
| IL-4 Inhibitor |
| 2-Amino-4-(3,4-dihydroxyphenyl)-6-(4-fluorophenyl)nicotinonitrile |