287111-25-5

287111-25-5 structure

Name: Linoleic Acid-13C18
Chemical Name: Linoleic Acid-13C18
CAS Number: 287111-25-5
Molecular Formula: ₁₃C₁₈H₃₂O₂
Molecular Weight: 298.313
Catalog: Research Areas Cardiovascular Disease
Create Date: 2021-08-24 19:23:25
Modify Date: 2024-01-12 15:45:11
Linoleic acid-13C18 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

Name	Linoleic Acid-13C18
Synonyms	9,12-Octadecadienoic-1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18-13C18 acid, (9Z,12Z)- LINOLEIC ACID-13C18 (9Z,12Z)-(13C18)-9,12-Octadecadienoic acid cis-9,cis-12-Octadecadienoic acid-13C18 13C Labeled linoleic acid 13C Labeled telfairic acid 9-cis,12-cis-Linoleic acid-13C18 MFCD01075561

Description	Linoleic acid-13C18 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.