1053601-50-5

1053601-50-5 structure
1053601-50-5 structure
  • Name: Ac-hMCH(6–16)-NH2
  • Chemical Name: Ac-hMCH(6–16)-NH2
  • CAS Number: 1053601-50-5
  • Molecular Formula: C58H99N21O13S3
  • Molecular Weight: 1394.73
  • Catalog: Signaling Pathways GPCR/G Protein MCHR1 (GPR24)
  • Create Date: 2021-07-26 18:03:39
  • Modify Date: 2024-01-05 20:13:42
  • Ac-hMCH(6-16)-NH2 binds to and activates equally well both human MCH receptors present in the brain (non-selective agonist), with IC50 values of 0.16 nM and 2.7 nM for MCH-1R and MCH-2R[1].

Name Ac-hMCH(6–16)-NH2
Description Ac-hMCH(6-16)-NH2 binds to and activates equally well both human MCH receptors present in the brain (non-selective agonist), with IC50 values of 0.16 nM and 2.7 nM for MCH-1R and MCH-2R[1].
Related Catalog
In Vitro Ac-hMCH(6-16)-NH2 exhibits EC50 values of 20 nM and 98 nM for MCH-1R and MCH-2R in aequorin functional assay, respectively[1].
References

[1]. Maria A Bednarek, et al. Synthesis and biological evaluation in vitro of a selective, high potency peptide agonist of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1. J Biol Chem. 2002 Apr 19;277(16):13821-6.

Molecular Formula C58H99N21O13S3
Molecular Weight 1394.73
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