133575-27-6
133575-27-6 structure
- Name: Ara-F-NAD+
- Chemical Name: Ara-F-NAD+
- CAS Number: 133575-27-6
- Molecular Formula: C21H26FN7O13P2
- Molecular Weight: 665.42
- Catalog: Research Areas Neurological Disease
- Create Date: 2021-09-11 12:32:49
- Modify Date: 2024-01-09 00:33:22
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Ara-F-NAD+, an arabino analogue of NAD+, is a potent, slow-binding CD38 NADase inhibitor, with a Ki of 169 nM[1][2].
| Name | Ara-F-NAD+ |
|---|
| Description | Ara-F-NAD+, an arabino analogue of NAD+, is a potent, slow-binding CD38 NADase inhibitor, with a Ki of 169 nM[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | The leucoyte surface antigen CD38 has been shown to be an ecto-enzyme with multiple catalytic activities. It is principally a NAD+ glycohydrolase that transforms NAD+ into ADP-ribose and nicotinamide. CD38 is also able to produce small amounts of cyclic ADP-ribose (ADP-ribosyl cyclase activity) and to hydrolyse this cyclic metabolite into ADP-ribose (cyclic ADP-ribose hydrolase activity)[1]. |
| References |
| Molecular Formula | C21H26FN7O13P2 |
|---|---|
| Molecular Weight | 665.42 |