Ara-F-NAD+
Modify Date: 2025-11-29 08:17:35
Ara-F-NAD+ structure
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Common Name | Ara-F-NAD+ | ||
|---|---|---|---|---|
| CAS Number | 133575-27-6 | Molecular Weight | 665.42 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H26FN7O13P2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ara-F-NAD+Ara-F-NAD+, an arabino analogue of NAD+, is a potent, slow-binding CD38 NADase inhibitor, with a Ki of 169 nM[1][2]. |
| Name | Ara-F-NAD+ |
|---|
| Description | Ara-F-NAD+, an arabino analogue of NAD+, is a potent, slow-binding CD38 NADase inhibitor, with a Ki of 169 nM[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | The leucoyte surface antigen CD38 has been shown to be an ecto-enzyme with multiple catalytic activities. It is principally a NAD+ glycohydrolase that transforms NAD+ into ADP-ribose and nicotinamide. CD38 is also able to produce small amounts of cyclic ADP-ribose (ADP-ribosyl cyclase activity) and to hydrolyse this cyclic metabolite into ADP-ribose (cyclic ADP-ribose hydrolase activity)[1]. |
| References |
| Molecular Formula | C21H26FN7O13P2 |
|---|---|
| Molecular Weight | 665.42 |
| InChIKey | JSGNSBZQCQQLEF-IVHCLJLKSA-N |
| SMILES | NC(=O)c1ccc[n+](C2OC(COP(=O)([O-])OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)C(O)C3O)C(O)C2F)c1 |