2287287-20-9

2287287-20-9 structure
2287287-20-9 structure
  • Name: Bromo-PEG1-NH2 hydrobromide
  • Chemical Name: Bromo-PEG1-NH2 hydrobromide
  • CAS Number: 2287287-20-9
  • Molecular Formula: C4H11Br2NO
  • Molecular Weight: 248.94
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-06-12 10:42:56
  • Modify Date: 2024-01-07 19:35:46
  • Bromo-PEG1-NH2 hydrobromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromo-PEG1-NH2 hydrobromide
Synonyms MFCD31794687
Description Bromo-PEG1-NH2 hydrobromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C4H11Br2NO
Molecular Weight 248.94