Bromo-PEG1-NH2 hydrobromide

Modify Date: 2024-01-07 19:35:46

Bromo-PEG1-NH2 hydrobromide Structure
Bromo-PEG1-NH2 hydrobromide structure
Common Name Bromo-PEG1-NH2 hydrobromide
CAS Number 2287287-20-9 Molecular Weight 248.94
Density N/A Boiling Point N/A
Molecular Formula C4H11Br2NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG1-NH2 hydrobromide


Bromo-PEG1-NH2 hydrobromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromo-PEG1-NH2 hydrobromide
Synonym More Synonyms

 Bromo-PEG1-NH2 hydrobromide Biological Activity

Description Bromo-PEG1-NH2 hydrobromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C4H11Br2NO
Molecular Weight 248.94

 Synonyms

MFCD31794687