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138194-55-5

138194-55-5 structure
138194-55-5 structure
  • Name: Mal-PFP ester
  • Chemical Name: Mal-PFP ester
  • CAS Number: 138194-55-5
  • Molecular Formula: C13H6F5NO4
  • Molecular Weight: 335.18
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-15 19:34:28
  • Modify Date: 2024-01-12 19:45:02
  • Mal-PFP ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-PFP ester
Description Mal-PFP ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C13H6F5NO4
Molecular Weight 335.18