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741235-80-3

741235-80-3 structure
741235-80-3 structure
  • Name: NH2-PEG2-methyl acetate
  • Chemical Name: NH2-PEG2-methyl acetate
  • CAS Number: 741235-80-3
  • Molecular Formula: C7H15NO4
  • Molecular Weight: 177.20
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-11 07:19:04
  • Modify Date: 2024-01-02 23:23:29
  • NH2-PEG2-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name NH2-PEG2-methyl acetate
Synonyms MFCD20718538
Description NH2-PEG2-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C7H15NO4
Molecular Weight 177.20