NH2-PEG2-methyl acetate

Modify Date: 2024-01-02 23:23:29

NH2-PEG2-methyl acetate Structure
NH2-PEG2-methyl acetate structure
Common Name NH2-PEG2-methyl acetate
CAS Number 741235-80-3 Molecular Weight 177.20
Density N/A Boiling Point N/A
Molecular Formula C7H15NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH2-PEG2-methyl acetate


NH2-PEG2-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name NH2-PEG2-methyl acetate
Synonym More Synonyms

 NH2-PEG2-methyl acetate Biological Activity

Description NH2-PEG2-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C7H15NO4
Molecular Weight 177.20

 Synonyms

MFCD20718538