883564-93-0

883564-93-0 structure
883564-93-0 structure
  • Name: t-Butyl acetate-PEG2-CH2COOH
  • Chemical Name: t-Butyl acetate-PEG2-CH2COOH
  • CAS Number: 883564-93-0
  • Molecular Formula: C12H22O7
  • Molecular Weight: 278.30
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-07-28 00:13:15
  • Modify Date: 2024-01-08 16:25:42
  • t-Butyl acetate-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name t-Butyl acetate-PEG2-CH2COOH
Synonyms MFCD31715330
Description t-Butyl acetate-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H22O7
Molecular Weight 278.30