t-Butyl acetate-PEG2-CH2COOH

Modify Date: 2024-01-08 16:25:42

t-Butyl acetate-PEG2-CH2COOH Structure
t-Butyl acetate-PEG2-CH2COOH structure
Common Name t-Butyl acetate-PEG2-CH2COOH
CAS Number 883564-93-0 Molecular Weight 278.30
Density N/A Boiling Point N/A
Molecular Formula C12H22O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Butyl acetate-PEG2-CH2COOH


t-Butyl acetate-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name t-Butyl acetate-PEG2-CH2COOH
Synonym More Synonyms

 t-Butyl acetate-PEG2-CH2COOH Biological Activity

Description t-Butyl acetate-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H22O7
Molecular Weight 278.30

 Synonyms

MFCD31715330