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2361138-33-0

2361138-33-0 structure
2361138-33-0 structure
  • Name: CCW16
  • Chemical Name: CCW16
  • CAS Number: 2361138-33-0
  • Molecular Formula: C22H20ClNO3
  • Molecular Weight: 381.852
  • Catalog: Research Areas Cancer
  • Create Date: 2021-09-14 08:55:44
  • Modify Date: 2024-01-11 19:13:37
  • CCW16 is the covalent ligand for the E3 ubiquitin ligase RNF4. CCW16 can be used in the synthesis of protein degraders[1].

Name CCW16
Synonyms Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)-
N-Benzyl-2-chloro-N-[4-(4-methoxyphenoxy)phenyl]acetamide
Description CCW16 is the covalent ligand for the E3 ubiquitin ligase RNF4. CCW16 can be used in the synthesis of protein degraders[1].
Related Catalog
References

[1]. Ward CC, et, al. Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440.

Density 1.2±0.1 g/cm3
Boiling Point 533.2±50.0 °C at 760 mmHg
Molecular Formula C22H20ClNO3
Molecular Weight 381.852
Flash Point 276.3±30.1 °C
Exact Mass 381.113159
LogP 3.66
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.617
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