CCW16

Modify Date: 2024-01-11 19:13:37

CCW16 Structure
CCW16 structure
Common Name CCW16
CAS Number 2361138-33-0 Molecular Weight 381.852
Density 1.2±0.1 g/cm3 Boiling Point 533.2±50.0 °C at 760 mmHg
Molecular Formula C22H20ClNO3 Melting Point N/A
MSDS N/A Flash Point 276.3±30.1 °C

 Use of CCW16


CCW16 is the covalent ligand for the E3 ubiquitin ligase RNF4. CCW16 can be used in the synthesis of protein degraders[1].

 Names

Name CCW16
Synonym More Synonyms

 CCW16 Biological Activity

Description CCW16 is the covalent ligand for the E3 ubiquitin ligase RNF4. CCW16 can be used in the synthesis of protein degraders[1].
Related Catalog
References

[1]. Ward CC, et, al. Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 533.2±50.0 °C at 760 mmHg
Molecular Formula C22H20ClNO3
Molecular Weight 381.852
Flash Point 276.3±30.1 °C
Exact Mass 381.113159
LogP 3.66
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.617

 Synonyms

Acetamide, 2-chloro-N-[4-(4-methoxyphenoxy)phenyl]-N-(phenylmethyl)-
N-Benzyl-2-chloro-N-[4-(4-methoxyphenoxy)phenyl]acetamide