29479-00-3

29479-00-3 structure

Name: Tabersonine hydrochloride
Chemical Name: (-)-tabersonine hydrochloride
CAS Number: 29479-00-3
Molecular Formula: C₂₁H₂₅ClN₂O₂
Molecular Weight: 372.88800
Catalog: Research Areas Inflammation/Immunology
Create Date: 2017-04-24 10:24:26
Modify Date: 2024-01-11 11:11:00
Tabersonine is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and is a potential therapeutic candidate for the treatment of ALI/ARDS[1].

Name	(-)-tabersonine hydrochloride
Synonyms	ent-2,3,6,7-Tetradehydro-aspidospermidin-3-carbonsaeure-methylester, Hydrochlorid ent-2,3,6,7-tetradehydro-aspidospermidine-3-carboxylic acid methyl ester, hydrochloride

Description	Tabersonine is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and is a potential therapeutic candidate for the treatment of ALI/ARDS[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Zhang D, et al. Tabersonine attenuates lipopolysaccharide-induced acute lung injury via suppressing TRAF6 ubiquitination. Biochem Pharmacol. 2018 Aug;154:183-192.