80576-77-8

80576-77-8 structure

Name: 10-methyl-10-deazaaminopterin
Chemical Name: N-{4-[1-(2,4-Diamino-6-pteridinyl)-2-propanyl]benzoyl}-L-glutamic acid
CAS Number: 80576-77-8
Molecular Formula: C₂₁H₂₃N₇O₅
Molecular Weight: 453.451
Catalog: Signaling Pathways Cell Cycle/DNA Damage Antifolate
Create Date: 2021-09-11 17:52:14
Modify Date: 2025-09-10 22:16:01
10-Methyl-10-deazaaminopterin is a folate analog and an antifolate. 10-Methyl-10-deazaaminopterin can be used for the research of cancer[1].

Name	N-{4-[1-(2,4-Diamino-6-pteridinyl)-2-propanyl]benzoyl}-L-glutamic acid
Synonyms	L-Glutamic acid, N-[4-[2-(2,4-diamino-6-pteridinyl)-1-methylethyl]benzoyl]- N-{4-[1-(2,4-Diamino-6-pteridinyl)-2-propanyl]benzoyl}-L-glutamic acid

Description	10-Methyl-10-deazaaminopterin is a folate analog and an antifolate. 10-Methyl-10-deazaaminopterin can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Antifolate
References	[1]. Sirotnak FM, et al. New folate analogs of the 10-deaza-aminopterin series. Further evidence for markedly increased antitumor efficacy compared with methotrexate in ascitic and solid murine tumor models. Cancer Chemother Pharmacol. 1984;12(1):26-30.