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100-74-3

100-74-3 structure
100-74-3 structure
  • Name: N-Ethylmorpholine
  • Chemical Name: N-Ethylmorpholine
  • CAS Number: 100-74-3
  • Molecular Formula: C6H13NO
  • Molecular Weight: 115.17400
  • Create Date: 2018-06-15 10:34:53
  • Modify Date: 2024-01-02 22:39:20

Name N-Ethylmorpholine
Synonyms MFCD00006177
4-Ethylmorpholine
EINECS 202-885-0
Density 0.91 g/mL at 20 °C(lit.)
Boiling Point 139 °C(lit.)
Melting Point −63 °C(lit.)
Molecular Formula C6H13NO
Molecular Weight 115.17400
Flash Point 82 °F
Exact Mass 115.10000
PSA 12.47000
LogP 0.27640
Vapour Pressure 6.36mmHg at 25°C
Index of Refraction n20/D 1.441(lit.)
Stability Stable. Flammable. Incompatible with strong oxidizing agents. Slightly air sensitive.
Water Solubility miscible
Freezing Point -63℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QE4025000
CHEMICAL NAME :
Morpholine, 4-ethyl-
CAS REGISTRY NUMBER :
100-74-3
BEILSTEIN REFERENCE NO. :
0102969
LAST UPDATED :
199806
DATA ITEMS CITED :
31
MOLECULAR FORMULA :
C6-H13-N-O
MOLECULAR WEIGHT :
115.20
WISWESSER LINE NOTATION :
T6N DOTJ A2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2000 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
18000 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9(Suppl 9),1,1987 *** REVIEWS *** ACGIH TLV-TWA 24 mg/m3 (5 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 20 ppm (94 mg/m3) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,113,1971 OSHA PEL (Gen Indu):8H TWA 20 ppm (94 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 20 ppm (94 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 20 ppm (94 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 20 ppm (94 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 ppm (23 mg/m3);Skin JAN 1993 OEL-BELGIUM:TWA 5 ppm (24 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 5 ppm (23.5 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 20 ppm (94 mg/m3);STEL 30 ppm (140 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 5 ppm (23 mg/m3);Skin JAN 1993 OEL-THE NETHERLANDS:TWA 5 ppm (23 mg/m3);Skin JAN 1993 OEL-THE PHILIPPINES:TWA 20 ppm (94 mg/m3);Skin JAN 1993 OEL-RUSSIA:STEL 5 mg/m3;Skin JAN 1993 OEL-SWEDEN:TWA 2 ppm (25 mg/m3);STEL 10 ppm (50 mg/m3);Skin JAN 1993 OEL-SWITZERLAND:TWA 5 ppm (25 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 5 ppm (23 mg/m3);STEL 20 ppm;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO N-ETHYLMORPHOLINE-air:10H TWA 5 ppm (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 32840 No. of Facilities: 37 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 967 (estimated)
Symbol GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
Signal Word Danger
Hazard Statements H226-H302 + H332-H311-H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R10;R21/22;R34
Safety Phrases S26-S36/37/39-S45-S16
RIDADR UN 2920 8/PG 2
WGK Germany 1
RTECS QE4025000
Packaging Group II
Hazard Class 8
HS Code 29349990
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%