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  • Product Name: NSC63871
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144-80-9

144-80-9 structure
144-80-9 structure

Name sulfacetamide
Synonyms A-500
N-(4-Aminobenzenesulfonyl)acetamide (N-(4-Aminophenylsulfonyl)acetamide
Solfacetamide [DCIT]
Alesten
EINECS 205-640-6
Acetocid
Oclucid
Sulamyd
N-[(4-Aminophenyl)sulfonyl]acetamide
sulfacetamidum
ALBUCID SOLUBLE
Acetamide, N-[(4-aminophenyl)sulfonyl]-
N-Acetylsulfanilamide
Sebizon
sultrin
N1-acetylsulfanilamide
I-Sulfacet
Prontamid
Sulfacet
Sulfair
Acetamide, N-((4-aminophenyl)sulfonyl)-
Isopto-Cetamide
N-acetyl-4-aminobenzenesulfonamide
sulfacetamide
Locula
Ak-Sulf
sulfacetamida
N-((4-Aminophenyl)sulfonyl)acetamide
Sulfacetimide
Region
Beocid-isoptal
Antebor
Albucid
MFCD00066501
Sulf-10
Description Sulfacetamide (Sulphacetamide), a bacteriostatic sulphonamide, is a popular antibiotic prescribed for treating ocular infections[1][2].
Related Catalog
References

[1]. D Smit. Anti-infective ophthalmic preparations in general practice, South African Family Practice, 54:4, 302-307.

[2]. N. Rajesh Goud,et al. Modulating the solubility of sulfacetamide by means of cocrystals†

Density 1.4±0.1 g/cm3
Melting Point 182-184 °C
Molecular Formula C8H10N2O3S
Molecular Weight 214.242
Exact Mass 214.041214
PSA 97.64000
LogP -0.96
Vapour Pressure 0.04mmHg at 25°C
Index of Refraction 1.584
Storage condition 0-6°C
Stability Stable. Incompatible with strong oxidizing agents, strong bases, strong reducing agents, strong acids.
Water Solubility <0.01 g/100 mL at 16 ºC

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AC8450000
CHEMICAL NAME :
Acetamide, N-sulfanilyl-
CAS REGISTRY NUMBER :
144-80-9
BEILSTEIN REFERENCE NO. :
0981718
LAST UPDATED :
199701
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C8-H10-N2-O3-S
MOLECULAR WEIGHT :
214.26
WISWESSER LINE NOTATION :
ZR DSWMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
16500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
606 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
8 gm/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - rigidity (including catalepsy)
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Behavioral - rigidity (including catalepsy) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
10 gm/kg
SEX/DURATION :
female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
1 gm/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80537 No. of Facilities: 68 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 2770 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80537 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1639 (estimated) No. of Female Employees: 1344 (estimated)
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R20/21/22
Safety Phrases S22-S24/25
RIDADR 3249
WGK Germany 2
RTECS AC8450000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2935009090
HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%