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86770-73-2

86770-73-2 structure
86770-73-2 structure
  • Name: Benzyl-PEG6-azide
  • Chemical Name: 19-azido-1-phenyl-2,5,8,11,14,17-hexaoxanonadecane
  • CAS Number: 86770-73-2
  • Molecular Formula: C19H31N3O6
  • Molecular Weight: 397.46600
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-04-03 06:30:02
  • Modify Date: 2024-01-09 10:02:26
  • Benzyl-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 19-azido-1-phenyl-2,5,8,11,14,17-hexaoxanonadecane
Synonyms Benzyl-PEG6-azide
Description Benzyl-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C19H31N3O6
Molecular Weight 397.46600
Exact Mass 397.22100
PSA 105.13000
LogP 2.04926
Precursor  0

DownStream  1