19388-87-5

19388-87-5 structure

Name: Taurolidine
Chemical Name: Taurolidine
CAS Number: 19388-87-5
Molecular Formula: C₇H₁₆N₄O₄S₂
Molecular Weight: 284.356
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-06-16 18:05:03
Modify Date: 2024-01-02 19:38:27
Taurolidine is a broad-spectrum antimicrobial for the prevention of central venous catheter-related infections. Taurolidine has a direct and selective antineoplastic effect on brain tumor cells by the induction of apoptosis[1].

Name	Taurolidine
Synonyms	4,4'-Methylenebis(tetrahydro-1,2,4-thiadiazine) 1,1,1',1'-tetraoxide 4,4'-methanediylbis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide 2H-1,2,4-Thiadiazine, 4,4'-methylenebis[tetrahydro-, 1,1,1',1'-tetraoxide 4,4'-Methylenebis(tetrahydro-1,2,4-sulfadiazine 1,1-dioxide) 4,4'-Methylenebis(perhydro-1,2,4-thiadiazine 1,1-dioxide) Bis(1,1-dioxoperhydro-1,2,4-thiadiazin-4-yl)methane 4,4'-Methylenebis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide Taurolin Taurolidine Tauroline

Description	Taurolidine is a broad-spectrum antimicrobial for the prevention of central venous catheter-related infections. Taurolidine has a direct and selective antineoplastic effect on brain tumor cells by the induction of apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Haro C, et al. Taurolidine, an antiseptic for the prevention of central venous catheter-related infections. Rev Chilena Infectol. 2019 Aug;36(4):414-420. [2]. Stendel R, et al. Treatment of glioblastoma with intravenous taurolidine. First clinical experience. Anticancer Res. 2004 Mar-Apr;24(2C):1143-7.

Density	1.5±0.1 g/cm3
Boiling Point	471.2±55.0 °C at 760 mmHg
Melting Point	156ºC
Molecular Formula	C₇H₁₆N₄O₄S₂
Molecular Weight	284.356
Flash Point	238.8±31.5 °C
Exact Mass	284.061310
PSA	115.58000
LogP	-2.55
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.564

RIDADR	NONH for all modes of transport
HS Code	2933990090

50-00-0

1378969-27-7

~72%

19388-87-5

Literature: BIOPHORE INDIA PHARMACEUTICALS PVT. LTD.; Pullagurla, Manik Reddy; Rangisetty, Jagadeesh Babu; Dokula, Neelam Naidu Patent: US2013/237700 A1, 2013 ; Location in patent: Paragraph 0028 ;

Precursor 2
50-00-0 1378969-27-7
DownStream 1
18996-35-5

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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