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1678-53-1

1678-53-1 structure
1678-53-1 structure

Name 4-Nitro-3-methylpyridine
Synonyms 3-Methyl-4-nitropyridine
MFCD04112532
3-Picoline, 4-nitro-
4-Nitro-3-picoline
Pyridine, 3-methyl-4-nitro-
Density 1.2±0.1 g/cm3
Boiling Point 244.2±20.0 °C at 760 mmHg
Melting Point 246 °C
Molecular Formula C6H6N2O2
Molecular Weight 138.124
Flash Point 101.5±21.8 °C
Exact Mass 138.042923
PSA 58.71000
LogP 0.79
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.558
Storage condition 2-8°C
Water Solubility 0.02 g/100 mL (20 ºC)
Name: 4-Nitro-3-picoline Material Safety Data Sheet
Synonym: 3-Methyl-4-nitropyridin
CAS: 1678-53-1
Section 1 - Chemical Product MSDS Name:4-Nitro-3-picoline Material Safety Data Sheet
Synonym:3-Methyl-4-nitropyridin

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
1678-53-1 4-Nitro-3-picoline unlisted
Hazard Symbols: XN
Risk Phrases: 21/22 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1678-53-1: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: cream
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C6H6N2O2
Molecular Weight: 138.12

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, acid chlorides, acid anhydrides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 1678-53-1 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
4-Nitro-3-picoline - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 21/22 Harmful in contact with skin and if
swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 1678-53-1: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 1678-53-1 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1678-53-1 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Hazard Codes Xn
Risk Phrases R10:Flammable. R22:Harmful if swallowed.
Safety Phrases S13-S25-S46
RIDADR 1332
RTECS XF9900000
Packaging Group III
Hazard Class 4.1
HS Code 2933399090

~83%

1678-53-1 structure

1678-53-1

Literature: Dormoy, Jean-Robert; Heymes, Alain Tetrahedron, 1993 , vol. 49, # 14 p. 2885 - 2914

~%

1678-53-1 structure

1678-53-1

Literature: Journal of Organometallic Chemistry, , vol. 517, # 1-2 p. 25 - 36

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1678-53-1 structure

1678-53-1

Literature: Journal of the American Chemical Society, , vol. 76, p. 3167
HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%