186142-28-9

186142-28-9 structure

186142-28-9 structure

Name: (Asn⁶⁷⁰,Leu6⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (667-676) trifluoroacetate salt
Chemical Name: [Asn670,Leu671]-Amyloid β/A4 Protein Precursor770 (667-676)
CAS Number: 186142-28-9
Molecular Formula: C₅₀H₇₈N₁₄O₁₉
Molecular Weight: 1179.237
Catalog: Biochemical Peptide
Create Date: 2018-07-17 19:41:51
Modify Date: 2025-08-25 06:35:45
SEVNLDAEFR is a substrate for BACE1[1].

Name	[Asn670,Leu671]-Amyloid β/A4 Protein Precursor770 (667-676)
Synonyms	(ASN670,LEU671)-APP770 (667-676) H-Ser-Glu-Val-Asn SEVNLDAEFR A4 PROTEIN PRECURSOR770 (667-676) SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG H-SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG-OH MFCD03097426 (Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-676)

Description	SEVNLDAEFR is a substrate for BACE1[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Beta-secretase Research Areas >> Neurological Disease
Target	BACE1[1]
References	[1]. Machálková M, et al. A label-free MALDI TOF MS-based method for studying the kinetics and inhibitor screening of the Alzheimer's disease drug target β-secretase. Anal Bioanal Chem. 2018 Nov;410(28):7441-7448.

Density	1.5±0.1 g/cm3
Molecular Formula	C₅₀H₇₈N₁₄O₁₉
Molecular Weight	1179.237
Exact Mass	1178.556763
PSA	562.34000
LogP	-1.78
Appearance	solid
Index of Refraction	1.646
Storage condition	−20°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3

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