100930-11-8

100930-11-8 structure

Name: [D-Trp2,7,9]-Substance P
Chemical Name: [D-Trp2,7,9]-Substance P
CAS Number: 100930-11-8
Molecular Formula: C₈₀H₁₀₉N₂₁O₁₃S
Molecular Weight: 1604.92000
Catalog: Signaling Pathways GPCR/G Protein Neurokinin Receptor
Create Date: 2019-02-17 10:27:52
Modify Date: 2024-07-17 19:53:58
[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist with Ki values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively[1].

Name	[D-Trp2,7,9]-Substance P
Synonyms	(d-trp2,7,9)-substance p arg-d-trp-lys-pro-gln-gln-d-trp-phe-d-trp-leu-met-nh2 h-arg-d-trp-lys-pro-gln-gln-d-trp-phe-d-trp-leu-met-nh2

Description	[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist with Ki values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
Target	NK1:1 μM (Ki) NK2:1.3 μM (Ki) NK3:~9 μM (Ki)
References	[1]. S H Buck, et al. Agonist and antagonist binding to tachykinin peptide NK-2 receptors. Life Sci. 1988;42(26):2701-8.