[D-Trp2,7,9]-Substance P

Modify Date: 2024-07-17 19:53:58

[D-Trp2,7,9]-Substance P Structure
[D-Trp2,7,9]-Substance P structure
 Common Name [D-Trp2,7,9]-Substance P
CAS Number 100930-11-8 Molecular Weight 1604.92000
Density N/A Boiling Point N/A
Molecular Formula C80H109N21O13S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of [D-Trp2,7,9]-Substance P


[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist with Ki values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively[1].

 Names

Name [D-Trp2,7,9]-Substance P
Synonym More Synonyms

 [D-Trp2,7,9]-Substance P Biological Activity

Description [D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist with Ki values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively[1].
Related Catalog
Target

NK1:1 μM (Ki)

NK2:1.3 μM (Ki)

NK3:~9 μM (Ki)

References

[1]. S H Buck, et al. Agonist and antagonist binding to tachykinin peptide NK-2 receptors. Life Sci. 1988;42(26):2701-8.  

 Chemical & Physical Properties

Molecular Formula C80H109N21O13S
Molecular Weight 1604.92000
Exact Mass 1603.82000
PSA 598.09000
LogP 8.43880

 Synonyms

(d-trp2,7,9)-substance p
arg-d-trp-lys-pro-gln-gln-d-trp-phe-d-trp-leu-met-nh2
h-arg-d-trp-lys-pro-gln-gln-d-trp-phe-d-trp-leu-met-nh2
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