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152743-19-6

152743-19-6 structure
152743-19-6 structure
  • Name: Nebadensin
  • Chemical Name: lysionotin
  • CAS Number: 152743-19-6
  • Molecular Formula: C18H16O7
  • Molecular Weight: 344.315
  • Catalog: API Synthetic anti-infective drugs Anti-tuberculosis leprosy
  • Create Date: 2018-04-18 08:00:00
  • Modify Date: 2025-08-19 20:20:03
  • Lysionotin is a flavonoid isolated from few flower lysionotus herbs. Lysionotin efficiently inhibit α-Toxin (a pore-forming protein) expression and shows significant protection against S. aureus in vitro and in vivo. Lysionotin has the potential for the treatment of S. aureus induced pneumonia[1].

Name lysionotin
Synonyms shidiaolanjiasu
Nebadensin
4H-1-Benzopyran-4-one, 5,7-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-
5,7-Dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
5,7-Dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
Description Lysionotin is a flavonoid isolated from few flower lysionotus herbs. Lysionotin efficiently inhibit α-Toxin (a pore-forming protein) expression and shows significant protection against S. aureus in vitro and in vivo. Lysionotin has the potential for the treatment of S. aureus induced pneumonia[1].
Related Catalog
Target

IC50: α-Toxin[1]

References

[1]. Teng Z, et al.Lysionotin attenuates Staphylococcus aureus pathogenicity by inhibiting α-toxin expression.Appl Microbiol Biotechnol. 2017 Sep;101(17):6697-6703.

Density 1.4±0.1 g/cm3
Boiling Point 615.0±55.0 °C at 760 mmHg
Molecular Formula C18H16O7
Molecular Weight 344.315
Flash Point 227.0±25.0 °C
Exact Mass 344.089600
PSA 98.36000
LogP 1.79
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.627
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