222315-88-0

222315-88-0 structure

Name: DP-b99
Chemical Name: 2,2'-{1,2-Ethanediylbis[oxy-2,1-phenylene({2-[2-(octyloxy)ethoxy]-2-oxoethyl}imino)]}diacetic acid
CAS Number: 222315-88-0
Molecular Formula: C₄₂H₆₄N₂O₁₂
Molecular Weight: 788.964
Catalog: Research Areas Neurological Disease
Create Date: 2021-09-12 22:13:48
Modify Date: 2025-08-25 18:11:27
DP-b99 is a chelator of zinc and calcium ions that acts selectively within cell membranes and has neuroprotective properties in animal models of stroke.

Name	2,2'-{1,2-Ethanediylbis[oxy-2,1-phenylene({2-[2-(octyloxy)ethoxy]-2-oxoethyl}imino)]}diacetic acid
Synonyms	2,2'-{1,2-Ethanediylbis[oxy-2,1-phenylene({2-[2-(octyloxy)ethoxy]-2-oxoethyl}imino)]}diacetic acid

Description	DP-b99 is a chelator of zinc and calcium ions that acts selectively within cell membranes and has neuroprotective properties in animal models of stroke.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Kalendarev T, Zupkovitz G, Ioffe V. The unusual gradient elution for reversed phase HPLC of a strong chelator as an active drug substance. J Pharm Biomed Anal. 2001;24(5-6):967-975. [2]. Diener HC, Schneider D, Lampl Y, Bornstein NM, Kozak A, Rosenberg G. DP-b99, a membrane-activated metal ion chelator, as neuroprotective therapy in ischemic stroke. Stroke. 2008;39(6):1774-1778.