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101-83-7

101-83-7 structure
101-83-7 structure
Name N-cyclohexylcyclohexanamine
Synonyms Bis(cyclohexyl)amine
EINECS 202-980-7
Dicyklohexylamin
Z-beta-tert-butyl-L-alanine·
(2S)-4-(tert-butoxy)-4-oxo-2-{[(prop-2-en-1-yloxy)carbonyl]amino}butanoic acid
Bis(Cyclohexyl)Amine
CYCLOHEXANAMINE,N-CYCLOHEXY
Cyclohexanamine, N-cyclohexyl
DCHA)DicyclohexylaM
Dodecahydrodiphenylamine
Dicyclohexylamin
Cyclohexanamine,N-cyclohexyl
Aminodicyclohexane
Boc-beta-cyclopropyl-L-Alanine·
(2S)-2-{[(tert-butoxy)carbonyl](methyl)amino}hexanoic acid
AK126767
(2R)-2-{[(tert-butoxy)carbonyl]amino}-5-methylhexanoic acid
2-[4-({[(2S,3R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}butanoyl]oxy}methyl)phenyl]acetic acid
DicyclohexylaM
(2S)-5-{[(tert-butoxy)carbonyl]amino}-2-{[(prop-2-en-1-yloxy)carbonyl]amino}pentanoic acid
DCHA
DicyclohexylaMine, ML
(2S,4R)-4-(tert-butoxy)-1-[(tert-butoxy)carbonyl]pyrrolidine-2-cboxylic acid
Perhydrodiphenylamine
MFCD00011658
Iminobis(cyclohexane)
DicylohexylamineForSynthesis
(2S)-2-{[(tert-butoxy)carbonyl]amino}-5-methylhexanoic acid
Dicha
N,N-Diclohexylamine
Boc-D-cyclopropylalanine·
(2R)-3-(4-{[(benzyloxy)carbonyl]amino}phenyl)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid
N-Cyclohexylcyclohexanamine
n-cyclohexyl-cyclohexanamin
di-cha
Dicyklohexylamin(DCHA)
2-{[(benzyloxy)carbonyl]amino}-3-cyclopropylpropanoic acid
N-cyclohexyl-Cyclohexanamine
(S)-Boc-2-amino-6-benzyloxy-hexanoic acid·
AURORA KA-7610
N,N-DICYCLOHEXYLAMINE
(2R)-2-{[(benzyloxy)carbonyl]amino}-5-{N'-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]cbamimidamido}pentanoic acid
biscyclohexylamine
(2S,4R)-Boc- 4-azido-pyrrolidine-2-cboxylic acid·
N-Cyclohexyl-cyclohexylamine
DICYCLOHEXYLAMINE (DCHA)
n,n-dicyclohexylamine
Dicyclohexylamine (DCHA)
DODECAHYDRODIPHENYLAMINE
Cyclohexylcyclohexanamine
dicyklohexylamin(czech)
Glipizide Impurity 19
(2S)-2-{[(tert-butoxy)carbonyl]amino}butanoic acid
DICYCLOHEXYLAMINE, 1000MG,NEAT
3-methoxy-2-[(2-methylpropan-2-yl)oxycbonylamino]propanoic acid
Bis(cyclohexyl)
Dicyclohexamine
(2S)-2-{[(tert-butoxy)carbonyl]amino}-6-{[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino}hexanoic acid
DICYCLOHEXYLAMINE
Density 0.9±0.1 g/cm3
Boiling Point 256.1±8.0 °C at 760 mmHg
Melting Point -2 °C
Molecular Formula C12H23N
Molecular Weight 181.318
Flash Point 96.1±0.0 °C
Exact Mass 181.183044
PSA 12.03000
LogP 3.69
Vapour density 6 (vs air)
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.488
Stability Stable. Incompatible with strong acids, strong oxidizing agents.
Water Solubility 1 g/L (20 ºC)
Freezing Point -2℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HY4025000
CHEMICAL NAME :
Dicyclohexylamine
CAS REGISTRY NUMBER :
101-83-7
BEILSTEIN REFERENCE NO. :
0605923
LAST UPDATED :
199710
DATA ITEMS CITED :
18
MOLECULAR FORMULA :
C12-H23-N
MOLECULAR WEIGHT :
181.36
WISWESSER LINE NOTATION :
L6TJ AM- AL6TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
373 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
135 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
40 gm/kg/52W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Liver - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2404 mg/kg/48W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Human Leukocyte
DOSE/DURATION :
200 ug/L
REFERENCE :
INHEAO Industrial Health. (National Institute of Industrial Health, 6-21-1 Nagao, Tama-ku, Kawasaki, 213 Japan) V.1- 1963- Volume(issue)/page/year: 9,188,1971 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 22,55,1980 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 22,55,1980 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,178,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1151 No. of Facilities: 60 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 368 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1151 No. of Facilities: 40 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 3412 (estimated) No. of Female Employees: 169 (estimated)
Symbol GHS05 GHS06 GHS09
GHS05, GHS06, GHS09
Signal Word Danger
Hazard Statements H301 + H311-H314-H410
Precautionary Statements P273-P280-P301 + P310 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;N:Dangerousfortheenvironment;
Risk Phrases R22;R34;R50/53
Safety Phrases S26-S36/37/39-S45-S60-S61
RIDADR UN 2565 8/PG 3
WGK Germany 2
RTECS HY4025000
Packaging Group III
Hazard Class 8
HS Code 2921300090
HS Code 2921300090
Summary 2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
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