89352-67-0

89352-67-0 structure

Name: ICI 174,864
Chemical Name: ici 174,864
CAS Number: 89352-67-0
Molecular Formula: C₃₄H₄₆N₄O₆
Molecular Weight: 606.75
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2017-04-20 03:29:49
Modify Date: 2024-02-04 11:14:02
ICI 174864 is a highly selective, potent δ-receptor antagonist. ICI 174864 is equipotent with naloxone and can not reverse the effect of the μ-agonist [D-Ala2, MePhe4, Gly-Ol5]enkephalin or the κ-agonist tifluadom[1].

Name	ici 174,864
Synonyms	N,N-DIALLYL-TYR-AIB-AIB-PHE-LEU Antalarmin hydrochloride N,N-Diallyl-Tyr-aib-Phe-Leu L-Leucine,N,N-di-2-propenyl-L-tyrosyl-2-methylalanyl-L-phenylalanyl

Description	ICI 174864 is a highly selective, potent δ-receptor antagonist. ICI 174864 is equipotent with naloxone and can not reverse the effect of the μ-agonist [D-Ala2, MePhe4, Gly-Ol5]enkephalin or the κ-agonist tifluadom[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
References	[1]. R Cotton, et, al. ICI 174864: a highly selective antagonist for the opioid delta-receptor. Eur J Pharmacol. 1984, 97,3.