126959-88-4

126959-88-4 structure

Name: Sar- [D-Phe8] -des-Arg9-Bradykinin
Chemical Name: [Sar,D-Phe8,des-Arg9]bradykinin
CAS Number: 126959-88-4
Molecular Formula: C₄₇H₆₆N₁₂O₁₁
Molecular Weight: 975.10
Catalog: Signaling Pathways GPCR/G Protein Bradykinin Receptor
Create Date: 2021-09-12 14:05:26
Modify Date: 2025-08-24 12:08:07
Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings[1].

Name	[Sar,D-Phe8,des-Arg9]bradykinin
Synonyms	[Sar,D-Phe8,des-Arg9]bradykinin D-Phenylalanine, N-methylglycyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl- N-Methylglycyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-D-phenylalanine

Description	Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings[1].
Related Catalog	Research Areas >> Endocrinology Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Bradykinin Receptor
References	[1]. Levesque L, et al. Regulation of kinin-induced contraction and DNA synthesis by inflammatory cytokines in the smooth muscle of the rabbit aorta. Br J Pharmacol. 1995 Sep;116(1):1673-9.