Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (22R)-14,20,22-Trihydroxy-1-oxoergosta-3,5,24-triene-18,26-dioic acid 18,20:26,22-dilactone
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Purity: 98.0%
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91599-21-2

91599-21-2 structure

Name: (22R)-14,20,22-Trihydroxy-1-oxoergosta-3,5,24-triene-18,26-dioic acid 18,20:26,22-dilactone
Chemical Name: 1-(4-Chlorophenyl)-2-methyl-6-phenyl-4(1H)-pyridinone
CAS Number: 91599-21-2
Molecular Formula: C₁₈H₁₄ClNO
Molecular Weight: 295.763
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2021-09-13 23:23:47
Modify Date: 2024-01-12 11:40:52
Withaphysalin D is a selective antagonist against the N-methyl-D-aspartate receptor (NMDAR) containing GluN2B. Withaphysalin D can be isolated from water lilies and has neuroprotective properties. Withaphysalin D is able to cross the blood-brain barrier[1].

Name	1-(4-Chlorophenyl)-2-methyl-6-phenyl-4(1H)-pyridinone
Synonyms	1-(4-Chlorophenyl)-2-methyl-6-phenyl-4(1H)-pyridinone 4(1H)-Pyridinone, 1-(4-chlorophenyl)-2-methyl-6-phenyl-

Description	Withaphysalin D is a selective antagonist against the N-methyl-D-aspartate receptor (NMDAR) containing GluN2B. Withaphysalin D can be isolated from water lilies and has neuroprotective properties. Withaphysalin D is able to cross the blood-brain barrier[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Kumar G,et al. Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: An in silico study. Med Hypotheses. 2016 Jul;92:35-43.