58028-00-5

58028-00-5 structure
58028-00-5 structure
  • Name: 1α-Hydroxy-3-epi-vitamin D3
  • Chemical Name: 1α-Hydroxy-3-epi-vitamin D3
  • CAS Number: 58028-00-5
  • Molecular Formula: C27H44O2
  • Molecular Weight: 400.64
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2021-09-05 07:05:03
  • Modify Date: 2024-01-10 17:44:23
  • 1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion[1].

Name 1α-Hydroxy-3-epi-vitamin D3
Description 1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion[1].
Related Catalog
In Vitro 1 alpha, 25(OH)2D3 is an important negative regulator of parathyroid hormone (PTH) gene transcription[1]. In ROS 17/2.8 cells, 1α-OHD3 (10 μM) not only metabolized into 1αOH-3-epi-D3 and 1α,25(OH)2D3 but also 1α,25(OH)2-3-epi-D3[2].
References

[1]. A J Brown, et al. 1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion. J Cell Biochem. 1999 Apr 1;73(1):106-13.

[2]. Alex J Brown, et al. Isolation and identification of 1alpha-hydroxy-3-epi-vitamin D3, a potent suppressor of parathyroid hormone secretion. J Cell Biochem

Molecular Formula C27H44O2
Molecular Weight 400.64