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1621096-79-4

1621096-79-4 structure
1621096-79-4 structure
  • Name: (E)-TCO-PEG4-NHS ester
  • Chemical Name: (E)-TCO-PEG4-NHS ester
  • CAS Number: 1621096-79-4
  • Molecular Formula: C24H38N2O10
  • Molecular Weight: 514.57
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-11 09:17:32
  • Modify Date: 2024-01-29 21:15:07
  • (E)-TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name (E)-TCO-PEG4-NHS ester
Description (E)-TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1013.

Molecular Formula C24H38N2O10
Molecular Weight 514.57