(E)-TCO-PEG4-NHS ester

Modify Date: 2024-01-29 21:15:07

(E)-TCO-PEG4-NHS ester Structure
(E)-TCO-PEG4-NHS ester structure
Common Name (E)-TCO-PEG4-NHS ester
CAS Number 1621096-79-4 Molecular Weight 514.57
Density N/A Boiling Point N/A
Molecular Formula C24H38N2O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (E)-TCO-PEG4-NHS ester


(E)-TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name (E)-TCO-PEG4-NHS ester

 (E)-TCO-PEG4-NHS ester Biological Activity

Description (E)-TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1013.

 Chemical & Physical Properties

Molecular Formula C24H38N2O10
Molecular Weight 514.57