Shanghai Nianxing Industrial Co., Ltd
China
Product Name: POT-4
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: POT-4
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

934461-40-2

934461-40-2 structure

934461-40-2 structure

Name: POT-4
Chemical Name: POT-4
CAS Number: 934461-40-2
Molecular Formula: C₇₂H₁₀₂N₂₂O₁₈S₂
Molecular Weight: 1627.85
Catalog: Signaling Pathways Immunology/Inflammation Complement System
Create Date: 2021-09-13 15:55:58
Modify Date: 2024-01-10 19:26:37
POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used for age-related macular degeneration research[1][2]

Name	POT-4

Description	POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used for age-related macular degeneration research[1][2]
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Complement System Research Areas >> Metabolic Disease
In Vitro	A derivative of compstatin, a potent C3 inhibitor, POT-4 is a cyclic peptide that exhibits binding activity to C3, preventing cleavage to its active fragments C3a and C3b[2].
References	[1]. S. Kaushal, et al. Complement C3 inhibitor POT-4: Clinical Safety of Intravitreal Administration. ARVO Annual Meeting Abstract, 2009 Apr. [2]. Robyn Troutbeck, et al. Therapeutic targeting of the complement system in age-related macular degeneration: a review. Clin Exp Ophthalmol. Jan-Feb 2012;40(1):18-26.

Molecular Formula	C₇₂H₁₀₂N₂₂O₁₈S₂
Molecular Weight	1627.85

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