Name | Thalidomide-O-C2-acid |
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Description | Thalidomide-O-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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Related Catalog | |
Target |
Cereblon |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
References |
Molecular Formula | C16H14N2O7 |
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Molecular Weight | 346.29 |
Hazard Codes | Xi |
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