2231760-33-9

2231760-33-9 structure
2231760-33-9 structure
  • Name: AZ2
  • Chemical Name: AZ2
  • CAS Number: 2231760-33-9
  • Molecular Formula: C20H23N3O2S
  • Molecular Weight: 369.48
  • Catalog: Signaling Pathways PI3K/Akt/mTOR PI3K
  • Create Date: 2021-09-29 08:51:37
  • Modify Date: 2024-01-13 11:07:20
  • AZ2 is a highly selective PI3Kγ inhibitor (The pIC50 value for PI3Kγ is 9.3). AZ2 can be used for the research of inflammatory and immune diseases[1].

Name AZ2
Description AZ2 is a highly selective PI3Kγ inhibitor (The pIC50 value for PI3Kγ is 9.3). AZ2 can be used for the research of inflammatory and immune diseases[1].
Related Catalog
Target

PI3Kγ:9.3 (pIC50)

PI3Kδ:6.6 (pIC50)

PI3Kα:5.1 (pIC50)

PI3Kβ:4.5 (pIC50)

In Vitro AZ2 (0.1~100 nM; 1 hour; SKOV-3 cells) excellent selectivity for PI3Kγ is further confirmed with a constitutively activated PI3K/Akt pathway[1].
References

[1]. Gangadhara G, et al. A class of highly selective inhibitors bind to an active state of PI3Kγ. Nat Chem Biol. 2019;15(4):348-357.

Molecular Formula C20H23N3O2S
Molecular Weight 369.48
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.