65113-67-9

65113-67-9 structure

Name: ACK
Chemical Name: H-Glu-Gly-Arg-chloromethylketone
CAS Number: 65113-67-9
Molecular Formula: C₁₄H₂₅ClN₆O₅
Molecular Weight: 392.83900
Catalog: Signaling Pathways Metabolic Enzyme/Protease PAI-1
Create Date: 2016-06-13 02:16:09
Modify Date: 2025-08-24 18:33:18
GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like serine protease urokinase-type plasminogen activator (uPA) inhibitor[1].

Name	H-Glu-Gly-Arg-chloromethylketone
Synonyms	glutamyl-glycyl-arginine chloromethyl ketone

Description	GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like serine protease urokinase-type plasminogen activator (uPA) inhibitor[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> PAI-1 Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Cancer
References	[1]. S Sperl, et al. (4-aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5113-8.