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10527-47-6

10527-47-6 structure
10527-47-6 structure
  • Name: Guanosine 5'-triphosphate-5'-adenosine
  • Chemical Name: Guanosine 5'-triphosphate-5'-adenosine
  • CAS Number: 10527-47-6
  • Molecular Formula: C20H27N10O17P3
  • Molecular Weight: 772.41
  • Catalog: Research Areas Others
  • Create Date: 2021-09-13 17:11:10
  • Modify Date: 2024-01-02 19:23:37
  • Guanosine 5'-triphosphate-5'-adenosine, the 5′ cap analog, is a fluorescent substrate analog[1].

Name Guanosine 5'-triphosphate-5'-adenosine
Description Guanosine 5'-triphosphate-5'-adenosine, the 5′ cap analog, is a fluorescent substrate analog[1].
Related Catalog
In Vitro Guanosine 5'-triphosphate-5'-adenosine (GpppA) labeled with pyrene at the 3′‐O position of adenosine acted as an artificial substrate[1]. Fluorescently labeled Guanosine 5'-triphosphate-5'-adenosine (GpppA) and GpppG analogs as potential substrates that represent a reasonable compromise between the structural complexity and requirements of the enzyme[1].
References

[1]. Renata Kasprzyk, et al. Direct High-Throughput Screening Assay for mRNA Cap Guanine-N7 Methyltransferase Activity. Chemistry. 2020 Sep 1;26(49):11266-11275.

[2]. Dennis Reichert, et al. Light-control of cap methylation and mRNA translation via genetic code expansion of Ecm1. Chem Sci. 2021 Feb 8;12(12):4383-4388.

Molecular Formula C20H27N10O17P3
Molecular Weight 772.41