Guanosine 5'-triphosphate-5'-adenosine

Modify Date: 2024-01-02 19:23:37

Guanosine 5'-triphosphate-5'-adenosine Structure
Guanosine 5'-triphosphate-5'-adenosine structure
Common Name Guanosine 5'-triphosphate-5'-adenosine
CAS Number 10527-47-6 Molecular Weight 772.41
Density N/A Boiling Point N/A
Molecular Formula C20H27N10O17P3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Guanosine 5'-triphosphate-5'-adenosine


Guanosine 5'-triphosphate-5'-adenosine, the 5′ cap analog, is a fluorescent substrate analog[1].

 Names

Name Guanosine 5'-triphosphate-5'-adenosine

 Guanosine 5'-triphosphate-5'-adenosine Biological Activity

Description Guanosine 5'-triphosphate-5'-adenosine, the 5′ cap analog, is a fluorescent substrate analog[1].
Related Catalog
In Vitro Guanosine 5'-triphosphate-5'-adenosine (GpppA) labeled with pyrene at the 3′‐O position of adenosine acted as an artificial substrate[1]. Fluorescently labeled Guanosine 5'-triphosphate-5'-adenosine (GpppA) and GpppG analogs as potential substrates that represent a reasonable compromise between the structural complexity and requirements of the enzyme[1].
References

[1]. Renata Kasprzyk, et al. Direct High-Throughput Screening Assay for mRNA Cap Guanine-N7 Methyltransferase Activity. Chemistry. 2020 Sep 1;26(49):11266-11275.

[2]. Dennis Reichert, et al. Light-control of cap methylation and mRNA translation via genetic code expansion of Ecm1. Chem Sci. 2021 Feb 8;12(12):4383-4388.

 Chemical & Physical Properties

Molecular Formula C20H27N10O17P3
Molecular Weight 772.41