Name | Pomalidomide-C3-NH2 hydrochloride |
---|---|
Synonyms | MFCD31729296 |
Description | Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
---|---|
Related Catalog | |
Target |
Cereblon |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
References |
Molecular Formula | C16H19ClN4O4 |
---|---|
Molecular Weight | 366.80 |
Hazard Codes | Xi |
---|