Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TAK-041
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Huang

ShangHai DC Chemicals Co.,Ltd
China
Product Name: TAK-041
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

DC Chemicals Limited
China
Product Name: TAK-041
Price: ￥1450.0/250mg ￥800.0/100mg ￥2900.0/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao

1929519-13-0

1929519-13-0 structure

1929519-13-0 structure

Name: TAK-041
Chemical Name: TAK-041
CAS Number: 1929519-13-0
Molecular Formula: C₁₈H₁₅F₃N₄O₃
Molecular Weight: 392.33
Catalog: Signaling Pathways GPCR/G Protein GPR139
Create Date: 2021-09-10 14:31:16
Modify Date: 2024-01-03 11:07:01
TAK-041 is a potent and selective GPR139 agonist with an EC50 of 22 nM. TAK-041 has the potential for the research of negative symptoms associated with schizophrenia[1].

Name	TAK-041

Description	TAK-041 is a potent and selective GPR139 agonist with an EC50 of 22 nM. TAK-041 has the potential for the research of negative symptoms associated with schizophrenia[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GPR139 Research Areas >> Neurological Disease
In Vivo	TAK-041 (0.03-3 mg/kg; P.o.) improves social behavior in BALB/c mice[1]. Animal Model: BALB/c mice[1] Dosage: 0.03, 0.3, and 3 mg/kg Administration: P.o. Result: Dose-dependently improved the social behavior of BALB/c mice.
References	[1]. Reichard HA, et al. Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with Schizophrenia [published online ahead of print, 2021 Jul 14]. J Med Chem. 2021;10.1021/acs.jmedchem.1c00820.

Molecular Formula	C₁₈H₁₅F₃N₄O₃
Molecular Weight	392.33