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1929519-13-0

1929519-13-0 structure
1929519-13-0 structure
  • Name: TAK-041
  • Chemical Name: TAK-041
  • CAS Number: 1929519-13-0
  • Molecular Formula: C18H15F3N4O3
  • Molecular Weight: 392.33
  • Catalog: Signaling Pathways GPCR/G Protein GPR139
  • Create Date: 2021-09-10 14:31:16
  • Modify Date: 2024-01-03 11:07:01
  • TAK-041 is a potent and selective GPR139 agonist with an EC50 of 22 nM. TAK-041 has the potential for the research of negative symptoms associated with schizophrenia[1].

Name TAK-041
Description TAK-041 is a potent and selective GPR139 agonist with an EC50 of 22 nM. TAK-041 has the potential for the research of negative symptoms associated with schizophrenia[1].
Related Catalog
In Vivo TAK-041 (0.03-3 mg/kg; P.o.) improves social behavior in BALB/c mice[1]. Animal Model: BALB/c mice[1] Dosage: 0.03, 0.3, and 3 mg/kg Administration: P.o. Result: Dose-dependently improved the social behavior of BALB/c mice.
References

[1]. Reichard HA, et al. Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with Schizophrenia [published online ahead of print, 2021 Jul 14]. J Med Chem. 2021;10.1021/acs.jmedchem.1c00820.

Molecular Formula C18H15F3N4O3
Molecular Weight 392.33
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