TAK-041

Modify Date: 2024-01-03 11:07:01

TAK-041 Structure
TAK-041 structure
Common Name TAK-041
CAS Number 1929519-13-0 Molecular Weight 392.33
Density N/A Boiling Point N/A
Molecular Formula C18H15F3N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TAK-041


TAK-041 is a potent and selective GPR139 agonist with an EC50 of 22 nM. TAK-041 has the potential for the research of negative symptoms associated with schizophrenia[1].

 Names

Name TAK-041

 TAK-041 Biological Activity

Description TAK-041 is a potent and selective GPR139 agonist with an EC50 of 22 nM. TAK-041 has the potential for the research of negative symptoms associated with schizophrenia[1].
Related Catalog
In Vivo TAK-041 (0.03-3 mg/kg; P.o.) improves social behavior in BALB/c mice[1]. Animal Model: BALB/c mice[1] Dosage: 0.03, 0.3, and 3 mg/kg Administration: P.o. Result: Dose-dependently improved the social behavior of BALB/c mice.
References

[1]. Reichard HA, et al. Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with Schizophrenia [published online ahead of print, 2021 Jul 14]. J Med Chem. 2021;10.1021/acs.jmedchem.1c00820.

 Chemical & Physical Properties

Molecular Formula C18H15F3N4O3
Molecular Weight 392.33
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Price: ¥3850/10 mM * 1 mL in DMSO

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