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1794938-87-6

1794938-87-6 structure

1794938-87-6 structure

Name: Epanolol-d5
Chemical Name: Epanolol-d5
CAS Number: 1794938-87-6
Molecular Formula: C₂₀H₁₈D₅N₃O₄
Molecular Weight: 374.45
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2021-11-01 23:17:07
Modify Date: 2024-01-13 18:56:18
Epanolol-d5 (Visacor-d5) is the deuterium labeled Epanolol. Epanolol (Visacor) is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors[1][2].

Name	Epanolol-d5

Description	Epanolol-d5 (Visacor-d5) is the deuterium labeled Epanolol. Epanolol (Visacor) is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Hosie J, et al. Pharmacokinetics of epanolol after acute and chronic oral dosing in elderly patients with stable angina pectoris. Br J Clin Pharmacol. 1990 Mar;29(3):333-7.

Molecular Formula	C₂₀H₁₈D₅N₃O₄
Molecular Weight	374.45