2410612-08-5
2410612-08-5 structure
- Name: FGFR1 inhibitor-2
- Chemical Name: FGFR1 inhibitor-2
- CAS Number: 2410612-08-5
- Molecular Formula: C25H22F5N3O3
- Molecular Weight: 507.45
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
- Create Date: 2021-10-25 22:24:42
- Modify Date: 2025-08-27 22:32:36
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FGFR1 inhibitor-2 is a FGFR1 inhibitor (IC50 is 4.55 μM in MDA-MB-231 cells). FGFR1 inhibitor-2 can be used for the research of metastatic triple-negative breast cancer[1].
| Name | FGFR1 inhibitor-2 |
|---|
| Description | FGFR1 inhibitor-2 is a FGFR1 inhibitor (IC50 is 4.55 μM in MDA-MB-231 cells). FGFR1 inhibitor-2 can be used for the research of metastatic triple-negative breast cancer[1]. |
|---|---|
| Related Catalog | |
| Target |
FGFR1 |
| In Vitro | FGFR1 inhibitor-2 (3 and 6 μM; 48 hours; MDA-MB-231) reduces the expression of FGFR1[1]. FGFR1 inhibitor-2 (0~5 μM; MDA-MB-231) increases the apoptotic index by 10.6-fold at 5 μM[1]. Western Blot Analysis[1] Cell Line: MDA-MB-231 Concentration: 3 and 6 μM Incubation Time: 48 hours Result: Reduced the expression of FGFR1. |
| References |
| Molecular Formula | C25H22F5N3O3 |
|---|---|
| Molecular Weight | 507.45 |