FGFR1 inhibitor-2

Modify Date: 2024-01-06 14:16:05

FGFR1 inhibitor-2 structure	Common Name	FGFR1 inhibitor-2
	CAS Number	2410612-08-5	Molecular Weight	507.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₂F₅N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FGFR1 inhibitor-2

FGFR1 inhibitor-2 is a FGFR1 inhibitor (IC50 is 4.55 μM in MDA-MB-231 cells). FGFR1 inhibitor-2 can be used for the research of metastatic triple-negative breast cancer[1].

Name	FGFR1 inhibitor-2

Description	FGFR1 inhibitor-2 is a FGFR1 inhibitor (IC50 is 4.55 μM in MDA-MB-231 cells). FGFR1 inhibitor-2 can be used for the research of metastatic triple-negative breast cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR
Target	FGFR1
In Vitro	FGFR1 inhibitor-2 (3 and 6 μM; 48 hours; MDA-MB-231) reduces the expression of FGFR1[1]. FGFR1 inhibitor-2 (0~5 μM; MDA-MB-231) increases the apoptotic index by 10.6-fold at 5 μM[1]. Western Blot Analysis[1] Cell Line: MDA-MB-231 Concentration: 3 and 6 μM Incubation Time: 48 hours Result: Reduced the expression of FGFR1.
References	[1]. Ashraf-Uz-Zaman M, et al. Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. Eur J Med Chem. 2021;209:112866.

Molecular Formula	C₂₅H₂₂F₅N₃O₃
Molecular Weight	507.45

DC Chemicals Limited
China
Product Name: FGFR1 inhibitor-2
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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